Industrial control computers (ICCs) require meticulous maintenance to ensure operational reliability, especially when removing software applications. Incomplete uninstallation can leave behind registry entries, configuration files, and service dependencies that may cause system conflicts, performance degradation, or security vulnerabilities. This guide provides detailed precautions for thoroughly cleaning software residues from ICC environments.

Follow manufacturer-recommended uninstallation procedures rather than simply deleting program folders. Key steps include:
Using the application's built-in uninstall utility (often found in the Start menu or program directory)
Running uninstallation as an administrator to ensure full system access
Verifying that all components are removed through progress indicators
Checking for confirmation messages indicating complete removal
A chemical plant experienced system instability after manually deleting a SCADA application folder instead of using its official uninstaller, leaving behind active services that conflicted with newly installed software.
The Windows registry often contains application-specific settings that require cleanup:
Backup the registry before making changes (using "regedit" export function)
Navigate to "HKEY_LOCAL_MACHINE\SOFTWARE" and "HKEY_CURRENT_USER\SOFTWARE" to locate application keys
Delete only entries clearly associated with the uninstalled software
Exercise caution with shared registry values that might affect other applications
An automotive assembly line avoided configuration errors by creating registry backups before removing legacy MES software entries, preventing accidental deletion of shared system parameters.
Beyond program directories, check these locations for residual files:
"ProgramData" folder for application-specific data
"AppData" subfolders (Local, LocalLow, Roaming) for user-specific configurations
Temporary files directories (usually in "Windows\Temp")
Shared system folders like "Common Files" for DLL dependencies
A power distribution company recovered 12GB of disk space by cleaning residual files from multiple uninstalled energy management applications, including hidden configuration files in the ProgramData directory.
Many industrial applications install background services that must be properly terminated:
Open "Services.msc" to review running services
Identify services associated with the uninstalled application
Stop services before removal and verify they don't restart automatically
Check for dependent services that might fail when primary services are removed
A water treatment facility prevented system crashes by manually stopping three interdependent services before uninstalling their legacy control software, avoiding automatic restart attempts that caused memory leaks.
Hardware-related software often installs device drivers that require special handling:
Open "Device Manager" to check for orphaned devices
Right-click and select "Uninstall device" for any remaining entries
Check for hidden devices using the "View > Show hidden devices" option
Verify that no residual drivers are consuming system resources
An oil refinery resolved communication errors with their PLC network by removing ghost drivers left behind after uninstalling obsolete fieldbus configuration software.
Applications may modify system environment variables that need restoration:
Open "System Properties > Advanced > Environment Variables"
Check both user and system variables for application-specific paths
Remove entries pointing to uninstalled software directories
Verify that PATH variable entries remain valid for other applications
A food processing plant corrected compilation errors in their control system by removing obsolete Java development kit paths from their system environment variables after uninstalling older development tools.
Many industrial applications create automated tasks that persist after uninstallation:
Open "Task Scheduler" to inspect all task libraries
Look for tasks with names matching the uninstalled application
Check for tasks that reference deleted file paths
Disable or delete orphaned tasks to prevent execution errors
A pharmaceutical company prevented daily error logs by removing 17 scheduled tasks left behind after uninstalling their quality control reporting software.
Application residues may remain in individual user profiles:
Navigate to "C:\Users[username]\AppData" for profile-specific data
Check "Local\Temp" and "Roaming" subfolders for application caches
Inspect "Start Menu" and "Desktop" for residual shortcuts
Consider creating a new user profile if cleanup proves too complex
A semiconductor manufacturer reduced login times by 40% after cleaning multiple user profiles of residual entries from uninstalled design automation tools.
Before major cleanup operations:
Create a manual system restore point ("Create a restore point" in System Properties)
Document the current system state including running processes
Verify the restore point contains all critical system files
Test the restore functionality before proceeding with extensive cleanup
A power generation plant avoided prolonged downtime by successfully restoring their system to a pre-cleanup state when an aggressive registry cleaning attempt accidentally disabled their HMI software.
Review and reset permissions modified by the uninstalled software:
Check folder permissions in Program Files and ProgramData
Verify registry key permissions haven't been altered
Ensure service accounts retain appropriate privileges
Restore default permissions where applications made changes
A transportation control center prevented unauthorized access attempts by auditing and resetting folder permissions that an uninstalled traffic management system had modified to grant excessive access rights.
Run security scans after cleanup to detect potential weaknesses:
Use enterprise vulnerability assessment tools
Check for open ports that might have been exposed by the application
Verify no residual services are listening on network interfaces
Ensure no unpatched components remain from the uninstalled software
A water management authority identified and patched a critical vulnerability in a legacy library that had been exposed when they uninstalled outdated water quality monitoring software.
Maintain records of all cleanup operations:
Document each step taken during the uninstallation process
Record registry keys and files removed
Note any system changes made during cleanup
Archive logs from monitoring tools used during the process
An energy distribution company maintained compliance with regulatory requirements by preserving detailed logs of their cleanup procedures when removing obsolete grid management software.
